Ariana Benedé Jover, Texans Depth Chart, who launched charity initiatives to raise funds, was the great catalyst for the project, which gave her real strength, the ARI program (Assistance Recerca Intensiva), promoted by a young woman who was diagnosed with the disease at the age of 13. . Ari, as she was known and for that reason the program with this name was baptized, she decided for her final high school work to organize a charity concert in 2015 and to allocate the funds to investigate the disease. That was the germ of the ARI project, which gave wings to another much more ambitious:
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There have been few novelties for triple negative breast cancer, but for others. The Pfizer drug has become a hopeful option for tumors with positive hormone receptors after more than ten years without any considerable advance in the therapeutic options available.
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The medication, taken in capsules, has offered an improvement in the quality of life of these patients who needed new treatment options. When the cancer is incurable, the goal is to turn it into a chronic disease and with simple handling. The treatment is based on three pillars: control the symptoms, prevent the progression of the disease and help maintain a good quality of life for as long as possible. This is what Ibrance brings.
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The clinical studies Paloma 1 and Paloma 2, which have evaluated this drug as a first-line treatment, have shown an absolute increase in the median survival of women with metastatic breast cancer compared to standard treatments.
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In addition, Spanish doctors have contributed fundamentally to its clinical development. Eighty-seven researchers from 66 hospital centers are participating in metastatic breast cancer studies with palbociclib and more than 700 patients have been recruited. The main national research groups such as Geicam and Solti have participated in a broad program of clinical trials. This, together with the implementation of the compassionate use program, is facilitating the treatment with palbociclib in patients with metastasis and breast cancer.
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The mean age of the patients diagnosed with metastasis at the first diagnosis is 65 years and most are postmenopausal, while the patients with early stage at diagnosis and later relapse at a distance from the disease are younger, with a median of age of 56 years, although they are still also mostly postmenopausal. That Dr. Pedro Cavadas (Valencia, 1965) is popularly known as “the miracle doctor” is not trivial. His medical career, marked by impossible transplants, and his humanistic facet make him worthy of the nickname and worldwide admiration.
the creation of the CAR-T Clinic Platform, from which, in addition to investigating and treating leukemia, it was thought that progress could also be made in the fight against other types of cancer. Only in 2017 the Texans Depth Chart program managed to raise more than one million euros. “Without ARI’s support, we would not have made it. The money has been coming when we needed it, “says Manuel Juan.